Interferon signaling suppresses the unfolded protein response and induces cell death in hepatocytes accumulating hepatitis B surface antigen

Virus infection, such as hepatitis B virus (HBV), occasionally causes endoplasmic reticulum (ER) stress. The unfolded protein response (UPR) is counteractive machinery to ER stress, and the failure of UPR to cope with ER stress results in cell death. Mechanisms that regulate the balance between ER s...

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Detalles Bibliográficos
Autores principales: Baudi, Ian, Isogawa, Masanori, Moalli, Federica, Onishi, Masaya, Kawashima, Keigo, Ishida, Yuji, Tateno, Chise, Sato, Yusuke, Harashima, Hideyoshi, Ito, Hiroyasu, Ishikawa, Tetsuya, Wakita, Takaji, Iannacone, Matteo, Tanaka, Yasuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143404/
https://www.ncbi.nlm.nih.gov/pubmed/33979382
http://dx.doi.org/10.1371/journal.ppat.1009228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143404/
https://www.ncbi.nlm.nih.gov/pubmed/33979382
http://dx.doi.org/10.1371/journal.ppat.1009228

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