Cargando…
Interferon signaling suppresses the unfolded protein response and induces cell death in hepatocytes accumulating hepatitis B surface antigen
Virus infection, such as hepatitis B virus (HBV), occasionally causes endoplasmic reticulum (ER) stress. The unfolded protein response (UPR) is counteractive machinery to ER stress, and the failure of UPR to cope with ER stress results in cell death. Mechanisms that regulate the balance between ER s...
Autores principales: | Baudi, Ian, Isogawa, Masanori, Moalli, Federica, Onishi, Masaya, Kawashima, Keigo, Ishida, Yuji, Tateno, Chise, Sato, Yusuke, Harashima, Hideyoshi, Ito, Hiroyasu, Ishikawa, Tetsuya, Wakita, Takaji, Iannacone, Matteo, Tanaka, Yasuhito |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143404/ https://www.ncbi.nlm.nih.gov/pubmed/33979382 http://dx.doi.org/10.1371/journal.ppat.1009228 |
Ejemplares similares
-
Restoration of type I interferon signaling in intrahepatically primed CD8(+) T cells promotes functional differentiation
por: Kawashima, Keigo, et al.
Publicado: (2021) -
HBV-Specific CD8+ T-Cell Tolerance in the Liver
por: Baudi, Ian, et al.
Publicado: (2021) -
Inhibitory Effect of a Human MicroRNA, miR-6133-5p, on the Fibrotic Activity of Hepatic Stellate Cells in Culture
por: Hamada-Tsutsumi, Susumu, et al.
Publicado: (2020) -
A Human Hepatocyte-Bearing Mouse: An Animal Model to Predict Drug Metabolism and Effectiveness in Humans
por: Yoshizato, Katsutoshi, et al.
Publicado: (2009) -
Genetic Variation of the IL-28B Promoter Affecting Gene Expression
por: Sugiyama, Masaya, et al.
Publicado: (2011)