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Application of a Physiologically Based Pharmacokinetic Model to Develop a Veterinary Amorphous Enrofloxacin Solid Dispersion

Zoonotic intestinal pathogens threaten human health and cause huge economic losses in farming. Enrofloxacin (ENR) shows high antibacterial activity against common intestinal bacteria. However, its poor palatability and low aqueous solubility limit the clinical application of ENR. To obtain an ENR or...

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Detalles Bibliográficos
Autores principales: Zhou, Kaixiang, Huo, Meixia, Ma, Wenjin, Mi, Kun, Xu, Xiangyue, Algharib, Samah Attia, Xie, Shuyu, Huang, Lingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143505/
https://www.ncbi.nlm.nih.gov/pubmed/33922109
http://dx.doi.org/10.3390/pharmaceutics13050602