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Application of a Physiologically Based Pharmacokinetic Model to Develop a Veterinary Amorphous Enrofloxacin Solid Dispersion
Zoonotic intestinal pathogens threaten human health and cause huge economic losses in farming. Enrofloxacin (ENR) shows high antibacterial activity against common intestinal bacteria. However, its poor palatability and low aqueous solubility limit the clinical application of ENR. To obtain an ENR or...
Autores principales: | Zhou, Kaixiang, Huo, Meixia, Ma, Wenjin, Mi, Kun, Xu, Xiangyue, Algharib, Samah Attia, Xie, Shuyu, Huang, Lingli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143505/ https://www.ncbi.nlm.nih.gov/pubmed/33922109 http://dx.doi.org/10.3390/pharmaceutics13050602 |
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