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The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia

The treatment of respiratory tract infections is threatened by the emergence of bacterial resistance. Immunomodulatory drugs, which enhance airway innate immune defenses, may improve therapeutic outcome. In this concept paper, we aim to highlight the utility of pharmacometrics and Bayesian inference...

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Detalles Bibliográficos
Autores principales: Michelet, Robin, Ursino, Moreno, Boulet, Sandrine, Franck, Sebastian, Casilag, Fiordiligie, Baldry, Mara, Rolff, Jens, van Dyk, Madelé, Wicha, Sebastian G., Sirard, Jean-Claude, Comets, Emmanuelle, Zohar, Sarah, Kloft, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143524/
https://www.ncbi.nlm.nih.gov/pubmed/33922017
http://dx.doi.org/10.3390/pharmaceutics13050601