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The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia
The treatment of respiratory tract infections is threatened by the emergence of bacterial resistance. Immunomodulatory drugs, which enhance airway innate immune defenses, may improve therapeutic outcome. In this concept paper, we aim to highlight the utility of pharmacometrics and Bayesian inference...
Autores principales: | Michelet, Robin, Ursino, Moreno, Boulet, Sandrine, Franck, Sebastian, Casilag, Fiordiligie, Baldry, Mara, Rolff, Jens, van Dyk, Madelé, Wicha, Sebastian G., Sirard, Jean-Claude, Comets, Emmanuelle, Zohar, Sarah, Kloft, Charlotte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143524/ https://www.ncbi.nlm.nih.gov/pubmed/33922017 http://dx.doi.org/10.3390/pharmaceutics13050601 |
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