The Mammalian and Yeast A49 and A34 Heterodimers: Homologous but Not the Same

Ribosomal RNA synthesis is the rate-limiting step in ribosome biogenesis. In eukaryotes, RNA polymerase I (Pol I) is responsible for transcribing the ribosomal DNA genes that reside in the nucleolus. Aberrations in Pol I activity have been linked to the development of multiple cancers and other gene...

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Detalles Bibliográficos
Autores principales: McNamar, Rachel, Rothblum, Katrina, Rothblum, Lawrence I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143541/
https://www.ncbi.nlm.nih.gov/pubmed/33921963
http://dx.doi.org/10.3390/genes12050620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143541/
https://www.ncbi.nlm.nih.gov/pubmed/33921963
http://dx.doi.org/10.3390/genes12050620

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