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The Mammalian and Yeast A49 and A34 Heterodimers: Homologous but Not the Same
Ribosomal RNA synthesis is the rate-limiting step in ribosome biogenesis. In eukaryotes, RNA polymerase I (Pol I) is responsible for transcribing the ribosomal DNA genes that reside in the nucleolus. Aberrations in Pol I activity have been linked to the development of multiple cancers and other gene...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143541/ https://www.ncbi.nlm.nih.gov/pubmed/33921963 http://dx.doi.org/10.3390/genes12050620 |