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Differential Complex Formation via Paralogs in the Human Sin3 Protein Interaction Network

Despite the continued analysis of HDAC inhibitors in clinical trials, the heterogeneous nature of the protein complexes they target limits our understanding of the beneficial and off-target effects associated with their application. Among the many HDAC protein complexes found within the cell, Sin3 c...

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Detalles Bibliográficos
Autores principales: Adams, Mark K., Banks, Charles A.S., Thornton, Janet L., Kempf, Cassandra G., Zhang, Ying, Miah, Sayem, Hao, Yan, Sardiu, Mihaela E., Killer, Maxime, Hattem, Gaye L., Murray, Alexis, Katt, Maria L., Florens, Laurence, Washburn, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143632/
https://www.ncbi.nlm.nih.gov/pubmed/32467258
http://dx.doi.org/10.1074/mcp.RA120.002078