Lappaol F, an anticancer agent, inhibits YAP via transcriptional and post-translational regulation

CONTEXT: Lappaol F (LAF), a natural lignan from Arctium lappa Linné (Asteraceae), inhibits tumour cell growth by inducing cell cycle arrest. However, its underlying anticancer mechanism remains unclear. OBJECTIVE: The effects of LAF on the Hippo-Yes-associated protein (YAP) signalling pathway, which...

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Detalles Bibliográficos
Autores principales: Li, Xiao, Lin, Yi-Ying, Tan, Jia-Yi, Liu, Kang-Lun, Shen, Xiao-Ling, Hu, Ying-Jie, Yang, Rui-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143639/
https://www.ncbi.nlm.nih.gov/pubmed/34010589
http://dx.doi.org/10.1080/13880209.2021.1923759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143639/
https://www.ncbi.nlm.nih.gov/pubmed/34010589
http://dx.doi.org/10.1080/13880209.2021.1923759

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