Measuring Site-specific Glycosylation Similarity between Influenza a Virus Variants with Statistical Certainty

Influenza A virus (IAV) mutates rapidly, resulting in antigenic drift and poor year-to-year vaccine effectiveness. One challenge in designing effective vaccines is that genetic mutations frequently cause amino acid variations in IAV envelope protein hemagglutinin (HA) that create new N-glycosylation...

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Detalles Bibliográficos
Autores principales: Chang, Deborah, Hackett, William E., Zhong, Lei, Wan, Xiu-Feng, Zaia, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143645/
https://www.ncbi.nlm.nih.gov/pubmed/32601173
http://dx.doi.org/10.1074/mcp.RA120.002031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143645/
https://www.ncbi.nlm.nih.gov/pubmed/32601173
http://dx.doi.org/10.1074/mcp.RA120.002031

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