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Down-regulation of immune checkpoints by doxorubicin and carboplatin-containing neoadjuvant regimens in a murine breast cancer model

OBJECTIVE(S): Immune checkpoint expression on tumor-infiltrating lymphocytes (TILs) has a correlation with the outcome of neoadjuvant chemotherapy (NAC) in breast cancer. However, the reciprocal effect of these regimens on the quality and quantity of immune checkpoints has hitherto not been addresse...

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Detalles Bibliográficos
Autores principales: Sadighi, Sanambar, Sharifian, Ramezanali, Kazemimanesh, Monireh, Muhammadnejad, Ahad, Shahosseini, Zahra, Amanpour, Saeid, Muhammadnejad, Samad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143709/
https://www.ncbi.nlm.nih.gov/pubmed/34094037
http://dx.doi.org/10.22038/ijbms.2021.54383.12221