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Pathogenic role of the SP/ NK1R system in GBM cells through inhibiting the thioredoxin system

OBJECTIVE(S): Glioblastoma multiforme (GBM), a highly aggressive Grade IV brain tumor, is a significant public health issue due to its poor prognosis and incurability. Neuropeptide substance P (SP) plays a critical role in GBM tumor growth and development via activation of neurokinin-1receptor (NK1R...

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Detalles Bibliográficos
Autores principales: Ghahremani, Fatemeh, Sabbaghzadeh, Reihaneh, Ebrahimi, Safieh, Javid, Hosein, Ghahremani, Javad, Hashemy, Seyed Isaac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143719/
https://www.ncbi.nlm.nih.gov/pubmed/34094032
http://dx.doi.org/10.22038/ijbms.2021.52902.11945