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Pathogenic role of the SP/ NK1R system in GBM cells through inhibiting the thioredoxin system
OBJECTIVE(S): Glioblastoma multiforme (GBM), a highly aggressive Grade IV brain tumor, is a significant public health issue due to its poor prognosis and incurability. Neuropeptide substance P (SP) plays a critical role in GBM tumor growth and development via activation of neurokinin-1receptor (NK1R...
Autores principales: | Ghahremani, Fatemeh, Sabbaghzadeh, Reihaneh, Ebrahimi, Safieh, Javid, Hosein, Ghahremani, Javad, Hashemy, Seyed Isaac |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143719/ https://www.ncbi.nlm.nih.gov/pubmed/34094032 http://dx.doi.org/10.22038/ijbms.2021.52902.11945 |
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