Pharmacokinetics and Bioavailability of Monomethyl Fumarate Following a Single Oral Dose of Bafiertam™ (Monomethyl Fumarate) or Tecfidera(®) (Dimethyl Fumarate)

BACKGROUND: Tecfidera(®) (dimethyl fumarate [DMF]) is an approved product for the treatment of relapsing forms of multiple sclerosis. Monomethyl fumarate (MMF) is the only active metabolite of DMF and is responsible for its therapeutic efficacy. OBJECTIVE: The objective of this study was to determin...

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Detalles Bibliográficos
Autores principales: Lategan, Thomas W., Wang, Laurene, Sprague, Tiffany N., Rousseau, Franck S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144082/
https://www.ncbi.nlm.nih.gov/pubmed/33797063
http://dx.doi.org/10.1007/s40263-021-00799-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144082/
https://www.ncbi.nlm.nih.gov/pubmed/33797063
http://dx.doi.org/10.1007/s40263-021-00799-9

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