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Pharmacokinetics and Bioavailability of Monomethyl Fumarate Following a Single Oral Dose of Bafiertam™ (Monomethyl Fumarate) or Tecfidera(®) (Dimethyl Fumarate)
BACKGROUND: Tecfidera(®) (dimethyl fumarate [DMF]) is an approved product for the treatment of relapsing forms of multiple sclerosis. Monomethyl fumarate (MMF) is the only active metabolite of DMF and is responsible for its therapeutic efficacy. OBJECTIVE: The objective of this study was to determin...
Autores principales: | Lategan, Thomas W., Wang, Laurene, Sprague, Tiffany N., Rousseau, Franck S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144082/ https://www.ncbi.nlm.nih.gov/pubmed/33797063 http://dx.doi.org/10.1007/s40263-021-00799-9 |
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