Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways

HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. It is characterized by aggressive behavior and treatment resistance. On the other hand, poly (amidoamine) (PAMAM) dendrimers are widely used in drug delivery systems and gene transfection a...

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Detalles Bibliográficos
Autores principales: Kheraldine, Hadeel, Gupta, Ishita, Alhussain, Hashim, Jabeen, Aayesha, Cyprian, Farhan S., Akhtar, Saghir, Al Moustafa, Ala-Eddin, Rachid, Ousama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144105/
https://www.ncbi.nlm.nih.gov/pubmed/34093999
http://dx.doi.org/10.1016/j.csbj.2021.05.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144105/
https://www.ncbi.nlm.nih.gov/pubmed/34093999
http://dx.doi.org/10.1016/j.csbj.2021.05.011

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