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The impact of technical failures on recombinant production of soluble proteins in Escherichia coli: a case study on process and protein robustness

Technical failures lead to deviations in process parameters that can exceed studied process boundaries. The impact on cell and target protein is often unknown. However, investigations on common technical failures might yield interesting insights into process and protein robustness. Recently, we publ...

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Detalles Bibliográficos
Autores principales: Pekarsky, Alexander, Reininger, Melanie, Spadiut, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144139/
https://www.ncbi.nlm.nih.gov/pubmed/33491129
http://dx.doi.org/10.1007/s00449-021-02514-w