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Vitamin D protects glomerular mesangial cells from high glucose-induced injury by repressing JAK/STAT signaling

AIM: High glucose (HG) induces the production of transforming growth factor (TGF)-β and reactive oxygen species, which further activates JAK/STAT signaling and promotes the synthesis of matrix proteins, contributes to the pathophysiological processes of diabetic nephropathy. This study aims to inves...

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Detalles Bibliográficos
Autores principales: Yang, Yiya, Lei, Yuting, Liang, Yumei, Fu, Shuangshuang, Yang, Congjun, Liu, Kanghan, Chen, Yinyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144147/
https://www.ncbi.nlm.nih.gov/pubmed/33942213
http://dx.doi.org/10.1007/s11255-020-02728-z