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PKC-phosphorylation of Liprin-α3 triggers phase separation and controls presynaptic active zone structure
The active zone of a presynaptic nerve terminal defines sites for neurotransmitter release. Its protein machinery may be organized through liquid–liquid phase separation, a mechanism for the formation of membrane-less subcellular compartments. Here, we show that the active zone protein Liprin-α3 rap...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144191/ https://www.ncbi.nlm.nih.gov/pubmed/34031393 http://dx.doi.org/10.1038/s41467-021-23116-w |