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Ethoxyquin is neuroprotective and partially prevents somatic and autonomic neuropathy in db/db mouse model of type 2 diabetes

Ethoxyquin (EQ), a quinolone-based antioxidant, has demonstrated neuroprotective properties against several neurotoxic drugs in a phenotypic screening and is shown to protect axons in animal models of chemotherapy-induced peripheral neuropathy. We assessed the effects of EQ on peripheral nerve funct...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Sun, Yuan, Ewaleifoh, Osefame, Wei, Josh, Mi, Ruifa, Zhu, Jing, Hoke, Ahmet, Polydefkis, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144207/
https://www.ncbi.nlm.nih.gov/pubmed/34031437
http://dx.doi.org/10.1038/s41598-021-89781-5