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Predicting MHC I restricted T cell epitopes in mice with NAP-CNB, a novel online tool

Lack of a dedicated integrated pipeline for neoantigen discovery in mice hinders cancer immunotherapy research. Novel sequential approaches through recurrent neural networks can improve the accuracy of T-cell epitope binding affinity predictions in mice, and a simplified variant selection process ca...

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Detalles Bibliográficos
Autores principales: Wert-Carvajal, Carlos, Sánchez-García, Rubén, Macías, José R, Sanz-Pamplona, Rebeca, Pérez, Almudena Méndez, Alemany, Ramon, Veiga, Esteban, Sorzano, Carlos Óscar S., Muñoz-Barrutia, Arrate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144223/
https://www.ncbi.nlm.nih.gov/pubmed/34031450
http://dx.doi.org/10.1038/s41598-021-89927-5