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Predicting MHC I restricted T cell epitopes in mice with NAP-CNB, a novel online tool
Lack of a dedicated integrated pipeline for neoantigen discovery in mice hinders cancer immunotherapy research. Novel sequential approaches through recurrent neural networks can improve the accuracy of T-cell epitope binding affinity predictions in mice, and a simplified variant selection process ca...
Autores principales: | Wert-Carvajal, Carlos, Sánchez-García, Rubén, Macías, José R, Sanz-Pamplona, Rebeca, Pérez, Almudena Méndez, Alemany, Ramon, Veiga, Esteban, Sorzano, Carlos Óscar S., Muñoz-Barrutia, Arrate |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144223/ https://www.ncbi.nlm.nih.gov/pubmed/34031450 http://dx.doi.org/10.1038/s41598-021-89927-5 |
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