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Tolerability and age‐dependent toxicokinetics following perinatal hydroxyurea treatment in Sprague Dawley rats

Hydroxyurea (HU) is a valuable therapy for individuals with sickle cell anemia. With increased use of HU in children and throughout their lives, it is important to understand the potential effects of HU therapy on their development and fertility. Thus, studies were conducted to identify appropriate...

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Detalles Bibliográficos
Autores principales: Huang, Madelyn C., Turner, Katie J., Vallant, Molly, Robinson, Veronica G., Lu, Yi, Price, Catherine J., Fennell, Timothy R., Silinski, Melanie A., Waidyanatha, Suramya, Ryan, Kristen R., Black, Sherry R., Fernando, Reshan A., McIntyre, Barry S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144245/
https://www.ncbi.nlm.nih.gov/pubmed/33241551
http://dx.doi.org/10.1002/jat.4087