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Tolerability and age‐dependent toxicokinetics following perinatal hydroxyurea treatment in Sprague Dawley rats
Hydroxyurea (HU) is a valuable therapy for individuals with sickle cell anemia. With increased use of HU in children and throughout their lives, it is important to understand the potential effects of HU therapy on their development and fertility. Thus, studies were conducted to identify appropriate...
Autores principales: | Huang, Madelyn C., Turner, Katie J., Vallant, Molly, Robinson, Veronica G., Lu, Yi, Price, Catherine J., Fennell, Timothy R., Silinski, Melanie A., Waidyanatha, Suramya, Ryan, Kristen R., Black, Sherry R., Fernando, Reshan A., McIntyre, Barry S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144245/ https://www.ncbi.nlm.nih.gov/pubmed/33241551 http://dx.doi.org/10.1002/jat.4087 |
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