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Clump sequencing exposes the spatial expression programs of intestinal secretory cells

Single-cell RNA sequencing combined with spatial information on landmark genes enables reconstruction of spatially-resolved tissue cell atlases. However, such approaches are challenging for rare cell types, since their mRNA contents are diluted in the spatial transcriptomics bulk measurements used f...

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Detalles Bibliográficos
Autores principales: Manco, Rita, Averbukh, Inna, Porat, Ziv, Bahar Halpern, Keren, Amit, Ido, Itzkovitz, Shalev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144370/
https://www.ncbi.nlm.nih.gov/pubmed/34031373
http://dx.doi.org/10.1038/s41467-021-23245-2