Improved methods for RNAseq-based alternative splicing analysis

The robust detection of disease-associated splice events from RNAseq data is challenging due to the potential confounding effect of gene expression levels and the often limited number of patients with relevant RNAseq data. Here we present a novel statistical approach to splicing outlier detection an...

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Detalles Bibliográficos
Autores principales: Halperin, Rebecca F., Hegde, Apurva, Lang, Jessica D., Raupach, Elizabeth A., Legendre, Christophe, Liang, Winnie S., LoRusso, Patricia M., Sekulic, Aleksandar, Sosman, Jeffrey A., Trent, Jeffrey M., Rangasamy, Sampathkumar, Pirrotte, Patrick, Schork, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144374/
https://www.ncbi.nlm.nih.gov/pubmed/34031440
http://dx.doi.org/10.1038/s41598-021-89938-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144374/
https://www.ncbi.nlm.nih.gov/pubmed/34031440
http://dx.doi.org/10.1038/s41598-021-89938-2

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