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Detecting and phasing minor single-nucleotide variants from long-read sequencing data

Cellular genetic heterogeneity is common in many biological conditions including cancer, microbiome, and co-infection of multiple pathogens. Detecting and phasing minor variants play an instrumental role in deciphering cellular genetic heterogeneity, but they are still difficult tasks because of tec...

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Detalles Bibliográficos
Autores principales: Feng, Zhixing, Clemente, Jose C., Wong, Brandon, Schadt, Eric E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144375/
https://www.ncbi.nlm.nih.gov/pubmed/34031367
http://dx.doi.org/10.1038/s41467-021-23289-4