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Detecting and phasing minor single-nucleotide variants from long-read sequencing data
Cellular genetic heterogeneity is common in many biological conditions including cancer, microbiome, and co-infection of multiple pathogens. Detecting and phasing minor variants play an instrumental role in deciphering cellular genetic heterogeneity, but they are still difficult tasks because of tec...
Autores principales: | Feng, Zhixing, Clemente, Jose C., Wong, Brandon, Schadt, Eric E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144375/ https://www.ncbi.nlm.nih.gov/pubmed/34031367 http://dx.doi.org/10.1038/s41467-021-23289-4 |
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