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Ultra-low dose immunization and multi-component vaccination strategies enhance protection against malaria in mice

An effective vaccine would be a valuable tool for malaria control and elimination; however, the leading malaria vaccine in development, RTS,S/AS01, provided only partial protection in a Phase 3 trial. R21 is a next-generation RTS,S-like vaccine. We have previously shown in mice that R21 administered...

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Detalles Bibliográficos
Autores principales: Collins, Katharine A., Brod, Florian, Snaith, Rebecca, Ulaszewska, Marta, Longley, Rhea J., Salman, Ahmed M., Gilbert, Sarah C., Spencer, Alexandra J., Franco, David, Ballou, W. Ripley, Hill, Adrian V. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144388/
https://www.ncbi.nlm.nih.gov/pubmed/34031479
http://dx.doi.org/10.1038/s41598-021-90290-8