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The inhibition of ABCB1/MDR1 or ABCG2/BCRP enables doxorubicin to eliminate liver cancer stem cells

Two ATP-binding cassette transporters, ABCB1/MDR1 and ABCG2/BCRP, are considered the most critical determinants for chemoresistance in hepatocellular carcinoma. However, their roles in the chemoresistance in liver cancer stem cells remain elusive. Here we explored the role of inhibition of MDR1 or A...

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Detalles Bibliográficos
Autores principales: Yin, Wang, Xiang, Dongxi, Wang, Tao, Zhang, Yumei, Pham, Cuong V., Zhou, Shufeng, Jiang, Guoqin, Hou, Yingchun, Zhu, Yimin, Han, Yinglu, Qiao, Liang, Tran, Phuong H.-L., Duan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144399/
https://www.ncbi.nlm.nih.gov/pubmed/34031441
http://dx.doi.org/10.1038/s41598-021-89931-9