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Topical arginase inhibition decreases growth of cutaneous squamous cell carcinoma

Cutaneous squamous cell carcinomas (cSCC) are among the most commonly diagnosed malignancies, causing significant morbidity and mortality. Tumor-associated macrophage (TAM) expression of arginase is implicated in tumor progression, and therapeutic use of arginase inhibitors has been studied in vario...

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Detalles Bibliográficos
Autores principales: Mittal, Amit, Wang, Mike, Vidyarthi, Aurobind, Yanez, Diana, Pizzurro, Gabriela, Thakral, Durga, Tracy, Erin, Colegio, Oscar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144401/
https://www.ncbi.nlm.nih.gov/pubmed/34031449
http://dx.doi.org/10.1038/s41598-021-90200-y