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Mining mutation contexts across the cancer genome to map tumor site of origin
The vast preponderance of somatic mutations in a typical cancer are either extremely rare or have never been previously recorded in available databases that track somatic mutations. These constitute a hidden genome that contrasts the relatively small number of mutations that occur frequently, the pr...
Autores principales: | Chakraborty, Saptarshi, Martin, Axel, Guan, Zoe, Begg, Colin B., Shen, Ronglai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144407/ https://www.ncbi.nlm.nih.gov/pubmed/34031376 http://dx.doi.org/10.1038/s41467-021-23094-z |
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