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Abiraterone induces SLCO1B3 expression in prostate cancer via microRNA-579-3p

Understanding mechanisms of resistance to abiraterone, one of the primary drugs approved for the treatment of castration resistant prostate cancer, remains a priority. The organic anion polypeptide 1B3 (OATP1B3, encoded by SLCO1B3) transporter has been shown to transport androgens into prostate canc...

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Detalles Bibliográficos
Autores principales: Barbier, Roberto H., McCrea, Edel M., Lee, Kristi Y., Strope, Jonathan D., Risdon, Emily N., Price, Douglas K., Chau, Cindy H., Figg, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144422/
https://www.ncbi.nlm.nih.gov/pubmed/34031488
http://dx.doi.org/10.1038/s41598-021-90143-4