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MPP8 is essential for sustaining self-renewal of ground-state pluripotent stem cells

Deciphering the mechanisms that control the pluripotent ground state is key for understanding embryonic development. Nonetheless, the epigenetic regulation of ground-state mouse embryonic stem cells (mESCs) is not fully understood. Here, we identify the epigenetic protein MPP8 as being essential for...

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Detalles Bibliográficos
Autores principales: Müller, Iris, Moroni, Ann Sophie, Shlyueva, Daria, Sahadevan, Sudeep, Schoof, Erwin M., Radzisheuskaya, Aliaksandra, Højfeldt, Jonas W., Tatar, Tülin, Koche, Richard P., Huang, Chang, Helin, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144423/
https://www.ncbi.nlm.nih.gov/pubmed/34031396
http://dx.doi.org/10.1038/s41467-021-23308-4