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Immunotranscriptomic profiling the acute and clearance phases of a human challenge dengue virus serotype 2 infection model

About 20–25% of dengue virus (DENV) infections become symptomatic ranging from self-limiting fever to shock. Immune gene expression changes during progression to severe dengue have been documented in hospitalized patients; however, baseline or kinetic information is difficult to standardize in natur...

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Detalles Bibliográficos
Autores principales: Hanley, John P., Tu, Huy A., Dragon, Julie A., Dickson, Dorothy M., Rio-Guerra, Roxana del, Tighe, Scott W., Eckstrom, Korin M., Selig, Nicholas, Scarpino, Samuel V., Whitehead, Stephen S., Durbin, Anna P., Pierce, Kristen K., Kirkpatrick, Beth D., Rizzo, Donna M., Frietze, Seth, Diehl, Sean A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144425/
https://www.ncbi.nlm.nih.gov/pubmed/34031380
http://dx.doi.org/10.1038/s41467-021-22930-6