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Power determination in vitamin D randomised control trials and characterising factors affecting it through a novel simulation-based tool
Thousands of observational studies have linked vitamin D deficiency with numerous diseases, but randomised controlled trials (RCTs) often fail to show benefit of supplementation. Population characteristics and trial design have long been suspected to undermine power but were not systematically inves...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144427/ https://www.ncbi.nlm.nih.gov/pubmed/34031451 http://dx.doi.org/10.1038/s41598-021-90019-7 |