Folliculin haploinsufficiency causes cellular dysfunction of pleural mesothelial cells

Birt–Hogg–Dubé syndrome (BHDS), an autosomal dominant inheritance disease caused by folliculin (FLCN) mutations, is associated with lung cysts and spontaneous pneumothorax. The possibility of FLCN haploinsufficiency in pleural mesothelial cells (PMCs) contributing to development of pneumothorax has...

Descripción completa

Detalles Bibliográficos
Autores principales: Okamoto, Shouichi, Ebana, Hiroki, Kurihara, Masatoshi, Mitani, Keiko, Kobayashi, Etsuko, Hayashi, Takuo, Sekimoto, Yasuhito, Nishino, Koichi, Otsuji, Mizuto, Kumasaka, Toshio, Takahashi, Kazuhisa, Seyama, Kuniaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144428/
https://www.ncbi.nlm.nih.gov/pubmed/34031471
http://dx.doi.org/10.1038/s41598-021-90184-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144428/
https://www.ncbi.nlm.nih.gov/pubmed/34031471
http://dx.doi.org/10.1038/s41598-021-90184-9

Ejemplares similares