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Extracellular pH affects the fluorescence lifetimes of metabolic co-factors

Significance: Autofluorescence measurements of the metabolic cofactors NADH and flavin adenine dinucleotide (FAD) provide a label-free method to quantify cellular metabolism. However, the effect of extracellular pH on flavin lifetimes is currently unknown. Aim: To quantify the relationship between e...

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Detalles Bibliográficos
Autores principales: Schmitz, Rebecca, Tweed, Kelsey, Walsh, Christine, Walsh, Alex J., Skala, Melissa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144436/
https://www.ncbi.nlm.nih.gov/pubmed/34032035
http://dx.doi.org/10.1117/1.JBO.26.5.056502