Targeted Therapy With PI3K and FGFR Inhibitors on Human Papillomavirus Positive and Negative Tonsillar and Base of Tongue Cancer Lines With and Without Corresponding Mutations

OBJECTIVES: Human papillomavirus positive (HPV(+)) tonsillar and base of tongue squamous cell carcinoma (TSCC/BOTSCC), the major subsites of oropharyngeal squamous cell carcinoma (OPSCC) have favorable outcome, but upon relapse, outcome is poor and new therapies needed. Since, phosphatidyl-inositol-...

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Detalles Bibliográficos
Autores principales: Holzhauser, Stefan, Wild, Nicole, Zupancic, Mark, Ursu, Ramona G., Bersani, Cinzia, Näsman, Anders, Kostopoulou, Ourania N., Dalianis, Tina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144504/
https://www.ncbi.nlm.nih.gov/pubmed/34046344
http://dx.doi.org/10.3389/fonc.2021.640490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144504/
https://www.ncbi.nlm.nih.gov/pubmed/34046344
http://dx.doi.org/10.3389/fonc.2021.640490

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