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Targeted Therapy With PI3K and FGFR Inhibitors on Human Papillomavirus Positive and Negative Tonsillar and Base of Tongue Cancer Lines With and Without Corresponding Mutations

OBJECTIVES: Human papillomavirus positive (HPV(+)) tonsillar and base of tongue squamous cell carcinoma (TSCC/BOTSCC), the major subsites of oropharyngeal squamous cell carcinoma (OPSCC) have favorable outcome, but upon relapse, outcome is poor and new therapies needed. Since, phosphatidyl-inositol-...

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Detalles Bibliográficos
Autores principales:	Holzhauser, Stefan, Wild, Nicole, Zupancic, Mark, Ursu, Ramona G., Bersani, Cinzia, Näsman, Anders, Kostopoulou, Ourania N., Dalianis, Tina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144504/ https://www.ncbi.nlm.nih.gov/pubmed/34046344 http://dx.doi.org/10.3389/fonc.2021.640490

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