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Andrographolide attenuates synovial inflammation of osteoarthritis by interacting with tumor necrosis factor receptor 2 trafficking in a rat model

BACKGROUND: Synovial inflammation plays a major role in the pathogenesis of osteoarthritis (OA). This study investigated the effect of andrographolide (Andro) on synovial inflammation mediated by tumor necrosis factor-alpha receptor 2 (TNFR2) trafficking and its utility in attenuating OA progression...

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Detalles Bibliográficos
Autores principales: Wang, Rongliang, Li, Jiawei, Xu, Xingquan, Xu, Jia, Jiang, Huiming, Lv, Zhongyang, Wu, Rui, Sun, Ziying, Guo, Wenjie, Sun, Yang, Ikegawa, Shiro, Jiang, Qing, Shi, Dongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144533/
https://www.ncbi.nlm.nih.gov/pubmed/34094861
http://dx.doi.org/10.1016/j.jot.2021.05.001