Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives

The SARS-CoV-2 pandemic has triggered global efforts to develop therapeutics. The main protease of SARS-CoV-2 (M(pro)), critical for viral replication, is a key target for therapeutic development. An organoselenium drug called ebselen has been demonstrated to have potent M(pro) inhibition and antivi...

Descripción completa

Detalles Bibliográficos
Autores principales: Amporndanai, Kangsa, Meng, Xiaoli, Shang, Weijuan, Jin, Zhenmig, Rogers, Michael, Zhao, Yao, Rao, Zihe, Liu, Zhi-Jie, Yang, Haitao, Zhang, Leike, O’Neill, Paul M., Samar Hasnain, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144557/
https://www.ncbi.nlm.nih.gov/pubmed/34031399
http://dx.doi.org/10.1038/s41467-021-23313-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144557/
https://www.ncbi.nlm.nih.gov/pubmed/34031399
http://dx.doi.org/10.1038/s41467-021-23313-7

Ejemplares similares