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Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics

Nasopharyngeal carcinoma (NPC) is a malignant head and neck cancer type with high morbidity in Southeast Asia, however the pathogenic mechanism of this disease is poorly understood. Using integrative pharmacogenomics, we find that NPC subtypes maintain distinct molecular features, drug responsivenes...

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Detalles Bibliográficos
Autores principales: Ding, Ren-Bo, Chen, Ping, Rajendran, Barani Kumar, Lyu, Xueying, Wang, Haitao, Bao, Jiaolin, Zeng, Jianming, Hao, Wenhui, Sun, Heng, Wong, Ada Hang-Heng, Valecha, Monica Vishnu, Yang, Eun Ju, Su, Sek Man, Choi, Tak Kan, Liu, Shuiming, Chan, Kin Iong, Yang, Ling-Lin, Wu, Jingbo, Miao, Kai, Chen, Qiang, Shim, Joong Sup, Xu, Xiaoling, Deng, Chu-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144567/
https://www.ncbi.nlm.nih.gov/pubmed/34031426
http://dx.doi.org/10.1038/s41467-021-23379-3