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Promises and challenges of adoptive T-cell therapies for solid tumours

Cancer is a leading cause of death worldwide and, despite new targeted therapies and immunotherapies, many patients with advanced-stage- or high-risk cancers still die, owing to metastatic disease. Adoptive T-cell therapy, involving the autologous or allogeneic transplant of tumour-infiltrating lymp...

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Detalles Bibliográficos
Autores principales: Morotti, Matteo, Albukhari, Ashwag, Alsaadi, Abdulkhaliq, Artibani, Mara, Brenton, James D., Curbishley, Stuart M., Dong, Tao, Dustin, Michael L., Hu, Zhiyuan, McGranahan, Nicholas, Miller, Martin L., Santana-Gonzalez, Laura, Seymour, Leonard W., Shi, Tingyan, Van Loo, Peter, Yau, Christopher, White, Helen, Wietek, Nina, Church, David N., Wedge, David C., Ahmed, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144577/
https://www.ncbi.nlm.nih.gov/pubmed/33782566
http://dx.doi.org/10.1038/s41416-021-01353-6