Integrated genomics and comprehensive validation reveal drivers of genomic evolution in esophageal adenocarcinoma

Esophageal adenocarcinoma (EAC) is associated with a marked genomic instability, which underlies disease progression and development of resistance to treatment. In this study, we used an integrated genomics approach to identify a genomic instability signature. Here we show that elevated expression o...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Subodh, Buon, Leutz, Talluri, Srikanth, Roncador, Marco, Liao, Chengcheng, Zhao, Jiangning, Shi, Jialan, Chakraborty, Chandraditya, Gonzalez, Gabriel, Tai, Yu-Tzu, Prabhala, Rao, Samur, Mehmet K., Munshi, Nikhil C., Shammas, Masood A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144613/
https://www.ncbi.nlm.nih.gov/pubmed/34031527
http://dx.doi.org/10.1038/s42003-021-02125-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144613/
https://www.ncbi.nlm.nih.gov/pubmed/34031527
http://dx.doi.org/10.1038/s42003-021-02125-x

Ejemplares similares