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Integrated genomics and comprehensive validation reveal drivers of genomic evolution in esophageal adenocarcinoma

Esophageal adenocarcinoma (EAC) is associated with a marked genomic instability, which underlies disease progression and development of resistance to treatment. In this study, we used an integrated genomics approach to identify a genomic instability signature. Here we show that elevated expression o...

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Detalles Bibliográficos
Autores principales:	Kumar, Subodh, Buon, Leutz, Talluri, Srikanth, Roncador, Marco, Liao, Chengcheng, Zhao, Jiangning, Shi, Jialan, Chakraborty, Chandraditya, Gonzalez, Gabriel, Tai, Yu-Tzu, Prabhala, Rao, Samur, Mehmet K., Munshi, Nikhil C., Shammas, Masood A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144613/ https://www.ncbi.nlm.nih.gov/pubmed/34031527 http://dx.doi.org/10.1038/s42003-021-02125-x

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