Lost in translation: no effect of repeated optogenetic cortico-striatal stimulation on compulsivity in rats

The orbitofrontal cortex–ventromedial striatum (OFC–VMS) circuitry is widely believed to drive compulsive behavior. Hyperactivating this pathway in inbred mice produces excessive and persistent self-grooming, which has been considered a model for human compulsivity. We aimed to replicate these findi...

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Detalles Bibliográficos
Autores principales: de Oliveira, Amanda R., Reimer, Adriano E., Simandl, Gregory J., Nagrale, Sumedh S., Widge, Alik S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144623/
https://www.ncbi.nlm.nih.gov/pubmed/34031365
http://dx.doi.org/10.1038/s41398-021-01448-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144623/
https://www.ncbi.nlm.nih.gov/pubmed/34031365
http://dx.doi.org/10.1038/s41398-021-01448-x

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