Up-Regulation of Immune Checkpoints in the Thymus of PRRSV-1-Infected Piglets in a Virulence-Dependent Fashion

Virulent porcine reproductive and respiratory syndrome virus (PRRSV) strains, such as the Lena strain, have demonstrated a higher thymus tropism than low virulent strains. Virulent PRRSV strains lead to severe thymus atrophy, which could be related to marked immune dysregulation. Impairment of T-cel...

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Detalles Bibliográficos
Autores principales: Ruedas-Torres, Inés, Rodríguez-Gómez, Irene M., Sánchez-Carvajal, José María, Guil-Luna, Silvia, Larenas-Muñoz, Fernanda, Pallarés, Francisco J., Carrasco, Librado, Gómez-Laguna, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144631/
https://www.ncbi.nlm.nih.gov/pubmed/34046040
http://dx.doi.org/10.3389/fimmu.2021.671743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144631/
https://www.ncbi.nlm.nih.gov/pubmed/34046040
http://dx.doi.org/10.3389/fimmu.2021.671743

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