Opposing functions for retromer and Rab11 in extracellular vesicle traffic at presynaptic terminals

Neuronal extracellular vesicles (EVs) play important roles in intercellular communication and pathogenic protein propagation in neurological disease. However, it remains unclear how cargoes are selectively packaged into neuronal EVs. Here, we show that loss of the endosomal retromer complex leads to...

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Detalles Bibliográficos
Autores principales: Walsh, Rylie B., Dresselhaus, Erica C., Becalska, Agata N., Zunitch, Matthew J., Blanchette, Cassandra R., Scalera, Amy L., Lemos, Tania, Lee, So Min, Apiki, Julia, Wang, ShiYu, Isaac, Berith, Yeh, Anna, Koles, Kate, Rodal, Avital A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144913/
https://www.ncbi.nlm.nih.gov/pubmed/34019080
http://dx.doi.org/10.1083/jcb.202012034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144913/
https://www.ncbi.nlm.nih.gov/pubmed/34019080
http://dx.doi.org/10.1083/jcb.202012034

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